Psychopathy linked to brain abnormalities

Psychopathy linked to brain abnormalities

Posted on 08/05/2012
Antisocialpuff

Images courtesy of Gregory, S. et al. ‘The Antisocial Brain’ (Archives of General Psychiatry)

New research provides the strongest evidence to date that psychopathy is linked to specific structural abnormalities in the brain. The study, led by researchers at King’s College London Institute of Psychiatry (IoP) is the first to confirm that psychopathy is a distinct neuro-developmental sub-group of anti-social personality disorder (ASPD).

The study was funded by the National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and the Institute of Psychiatry at King’s College London and published in Archives of General Psychiatry.

Most violent crimes are committed by a small group of persistent male offenders with ASPD. Approximately half of male prisoners in England and Wales will meet diagnostic criteria for ASPD. The majority of such men are not true psychopaths (ASPD-P). They are characterised by emotional instability, impulsivity and high levels of mood and anxiety disorders. They typically use aggression in a reactive way in response to a perceived threat or sense of frustration.  

However, about one third of such men will meet additional diagnostic criteria for psychopathy (ASPD+P). They are characterised by a lack of empathy and remorse, and use aggression in a planned way to secure what they want (status, money etc.). Previous research has shown that psychopaths’ brains differ structurally from healthy brains, but until now, none have examined these differences within a population of violent offenders with ASPD. 

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